BRAF V600D

含有缬氨酸600残基BRAF突变的患者对达巴芬尼敏感。有关V600轨迹的更多信息,请参见V600E条目。
Patients harboring mutations in valine 600 residue of BRAF have been shown to be sensitive to dabrafenib. For more information on the V600 locus, see the V600E entry.

别名

突变位点

Ref. Build: GRCh37   Ensembl Version: 75
Chr.StartStopRef. sVar. Bases
7140453135140453136CAAT
Transcript
ENST00000288602.6

基因序列

NM_004333.4:c.1799_1800delTGinsAT
NP_004324.2:p.Val600Asp
ENST00000288602.6:c.1799_1800delTGinsAT
NC_000007.13:g.140453135_140453136delinsAT