BTG1

这个基因是一个抗增殖基因家族的成员,它调节细胞的生长和分化。该基因在细胞周期g0/g1期表达最高,在细胞进入g1期时表达下调。编码蛋白与多种核受体相互作用,并作为细胞分化的共同激活因子。该位点与一例b细胞慢性淋巴细胞白血病的t(8;12)(q24;q22)染色体易位有关。[由RefSeq提供,2008年10月]
This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. [provided by RefSeq, Oct 2008]

别名

APRO2

基因id

Chromosome:12 Start: 92534054 End: 92539673 Strand: 

药物

突变与药物

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