EREG

该基因编码一种分泌肽激素和表皮生长因子(egf)蛋白家族成员。编码蛋白是表皮生长因子受体(egfr)和结构相关的erb-b2受体酪氨酸激酶4(erbb4)的配体。编码蛋白可能参与多种生物学过程,包括炎症、伤口愈合、卵母细胞成熟和细胞增殖。此外,编码蛋白可能促进各种人体组织癌症的进展。
This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues.

别名

EPR,ER,Ep

基因id

Chromosome:4 Start: 75230860 End: 75254468 Strand: 1

突变与药物

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