FOXO1

该基因属于转录因子的叉头家族,具有独特的叉头结构域。该基因的特异功能尚未确定,但可能在肌源性生长和分化中发挥作用。该基因与pax3的易位与肺泡横纹肌肉瘤有关。
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.

别名

FKH1,FKHR,FOXO1A

基因id

Chromosome:13 Start: 41129804 End: 41240734 Strand: -1

药物

Bromodomain Inhibitor 

突变与药物

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