HCK

这个基因编码的蛋白质是酪氨酸激酶src家族的成员。这种蛋白质主要是造血的,特别是在髓系和B淋巴细胞系的细胞中。它可能有助于将fc受体与呼吸爆发的激活结合起来。此外,它可能在中性粒细胞迁移和中性粒细胞脱颗粒中发挥作用。由于选择性剪接和选择性翻译起始密码子(包括非aug密码子)的使用,产生了具有不同亚细胞分布的多个亚型。[由RefSeq提供,2010年2月]
The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon. [provided by RefSeq, Feb 2010]

别名

JTK9,p59Hck,p61Hck

基因id

Chromosome:20 Start: 30639991 End: 30689659 Strand: 

药物

突变与药物

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