HMOX1

血红素加氧酶是血红素分解代谢中的一种重要酶,它将血红素分解成胆绿素,胆绿素还原酶和一氧化碳(一种公认的神经递质)随后将胆绿素转化为胆红素。血红素加氧酶活性是由底物血红素和各种非血红素物质诱导的。血红素加氧酶以2种同工酶、一种诱导性血红素加氧酶-1和一种组成性血红素加氧酶-2的形式存在。hmox1和hmox2属于血红素加氧酶家族。
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.

别名

HMOX1D,HO-1,HSP32,bK286B10

基因id

Chromosome:22 Start: 35776354 End: 35790207 Strand: 1

药物

突变与药物

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相关基因检测

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