Q56P 基因突变 MAP2K1癌基因 - 癌症123

基因突变

MAP2K1 突变位点基因序列 MAP2K1 Q56P MAP2K1 Q56P是黑色素瘤和胃癌的复发性突变。这种突变已被证明对AZD6244治疗黑色素瘤细胞株具有相当大的抵抗力。 MAP2K1 Q56P is a recurrent mutation in melanoma and gastric cancer. This mutation has been shown to confer considerable resistance to AZD6244 treatment of melanoma cell lines.

别名

GLN56PRO
Allele Registry ID：CA16602453
ClinVar ID：375978

突变位点

Ref. Build: GRCh37 Ensembl Version: 75

Chr.	Start	Stop	Ref. s	Var. Bases
15	66727451	66727451	A	C
Transcript
ENST00000307102.5

基因序列

ENST00000307102.5:c.167A>003eC
NC_000015.9:g.66727451A>003eC
NM_002755.3:c.167A>003eC
NP_002746.1:p.Gln56Pro