MAP3K14

该基因编码丝裂原活化蛋白激酶激酶14,是一种丝氨酸/苏氨酸蛋白激酶。这种激酶与traf2结合并刺激nf-kappab活性。它与其他几种mapkk激酶序列相似。它参与nf-kappab诱导的信号级联反应,与肿瘤坏死/神经生长因子(tnf/ngf)家族受体和白细胞介素-1型受体共有。[由RefSeq提供,2008年7月]
This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]

别名

HS,NIK,HSNIK,FTDCR1B

基因id

Chromosome:17 Start: 43340488 End: 43394414 Strand: 

药物

突变与药物

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