MPO

Myeloperoxidase(MPO)是髓系分化过程中合成的一种血红素蛋白,是嗜中性粒细胞嗜盐颗粒的主要成分。作为一个单链前体,髓过氧化物酶随后裂解成轻和重链。成熟髓过氧化物酶是由2个轻链和2个重链组成的四聚体。这种酶产生的次卤酸是中性粒细胞杀菌活性的核心。[由RefSeq提供,2014年11月]
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]

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Chromosome:17 Start: 56347217 End: 56358296 Strand: 

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突变与药物

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