B2 DOMAIN MUTATION 基因突变 PML癌基因 - 癌症123

基因突变

PML 突变位点基因序列 PML B2 DOMAIN MUTATION PML中的B2域是ATRA的结合位点。该区域的点突变与APL患者的ATRA抵抗有关。 The B2 domain in PML is the binding site for ATRA. Point mutations in this region have been associated with ATRA resistance in patients with APL.

别名

Allele Registry ID：
ClinVar ID：

突变位点

Ref. Build: GRCh37 Ensembl Version: 75

Chr.	Start	Stop	Ref. s	Var. Bases
15	74315213	74315219	C	T
Transcript
ENST00000268058.3

基因序列