RPS10

核糖体是催化蛋白质合成的细胞器,由一个小的40s亚基和一个大的60s亚基组成。这些亚基由4种RNA和大约80种结构上不同的蛋白质组成。这个基因编码一个核糖体蛋白,它是40S亚单位的一个组成部分该蛋白属于核糖体蛋白s10e家族。它位于细胞质中。与邻近的正常组织相比,该基因在结直肠癌中的表达是可变的,尽管没有发现表达水平与疾病的严重程度之间的相关性作为编码核糖体蛋白的典型基因,有多个经过处理的假基因散布在基因组中。交替剪接导致编码相同蛋白质的多个转录变体自然发生的读写转录发生在这个位点和邻近的位点nudt3(nudix(核苷二磷酸连接部分x)型基序3之间。[由refseq提供,2011年2月]
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S10E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternate splicing results in multiple transcript variants that encode the same protein. Naturally occurring read-through transcription occurs between this locus and the neighboring locus NUDT3 (nudix (nucleoside diphosphate linked moiety X)-type motif 3).[provided by RefSeq, Feb 2011]

别名

S10,DBA9

基因id

Chromosome:6 Start: 34385231 End: 34393902 Strand: 

药物

突变与药物

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