RUNX1 D198Y

D198Y在一个家族性血小板疾病病史的家系中观察到，该家族有急性髓性白血病的倾向。它发生在runx1的runt域内，已知与疾病有关。
D198Y was observed in a pedigree with a history of Familial platelet disorder with predisposition to acute myeloid leukemia. It occurs within the Runt domain of RUNX1, known to be associated with the disease.