ABCB1 I1145I

ABCB1I1145I是一种提高癌症应答的种系多态性。具体来说，它可以表明对非小细胞肺癌患者的铂基化疗的敏感性，或对HER2阳性转移性乳腺癌患者的更好疗效。
ABCB1 I1145I is a germline polymorphism that has improved responses in cancer. Specifically, it can indicate sensitivity to platinum-based chemotherapies for patients with NSCLC or better outcome for HER2-positive metastatic breast cancer patients.