BRF1

该基因编码rna聚合酶iii转录因子复合物的三个亚单位之一。这个复合物在RNA聚合酶III对编码tRNA、5srrna和其他小结构RNA的基因的转录起始中起着中心作用该基因产物属于tfb家族。已鉴定出几种编码不同亚型的选择性剪接变体，它们在由RNA聚合酶III转录的不同启动子处起作用[由RefSeq提供，2011年6月]
This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encoding tRNA, 5S rRNA, and other small structural RNAs. The gene product belongs to the TF2B family. Several alternatively spliced variants encoding different isoforms, that function at different promoters transcribed by RNA polymerase III, have been identified. [provided by RefSeq, Jun 2011]