BRIP1

该基因编码的蛋白质是recq-deah螺旋酶家族的成员,与乳腺癌1型(brca1)的brct重复序列相互作用。结合复合体在1型乳腺癌(brca1)正常双链断裂修复功能中起重要作用。这个基因可能是生殖系癌症诱发突变的靶点。[由RefSeq提供,2008年7月]
The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations. [provided by RefSeq, Jul 2008]

别名

OF,BACH1,FANCJ

基因id

Chromosome:17 Start: 59756547 End: 59940920 Strand: 

药物

突变与药物

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