ERBB4 MUTATION

在黑色素瘤、肺腺癌和髓母细胞瘤中发现了erbbb4突变。体外研究表明，含有erbb4突变的黑色素瘤细胞株对用拉帕替尼抑制erb4敏感。
ERBB4 mutations have been identified in melanoma, lung adenocarcinoma and medulloblastoma. In-vitro studies suggest that melanoma cell lines harboring an ERBB4 mutation are sensitive to ERBB4 inhibition with lapatinib.