ERG TMPRSS2-ERG

TMPRSS2融合在前列腺癌中很普遍。TMPRSS2与ETS家庭成员（如ERG）的融合是最常见的。TMPRSS2与ERG融合可能导致由TMPRSS2雄激素反应启动子元件驱动的ERG过度表达。由于这种融合的普遍性，它可能对前列腺癌，特别是ERG表达阳性的前列腺癌有诊断价值。
TMPRSS2 fusions are prevalent in Prostate Cancer. TMPRSS2 fusion with ETS family members such as ERG are among the most common. Fusion of TMPRSS2 with ERG may result in overexpression of ERG driven by the TMPRSS2 androgen-responsive promoter elements. Due to the high prevalence of this fusion, it may have diagnostic utility for prostate cancer, especially ERG expression positive prostate cancer.