FCRL4

该基因编码免疫球蛋白受体超家族的一个成员，是聚集在1号染色体长臂上的几种Fc受体样糖蛋白之一该编码蛋白具有四个细胞外c2型免疫球蛋白结构域、一个跨膜结构域和一个包含三个免疫受体酪氨酸抑制基序的细胞质结构域。这种蛋白可能在上皮内记忆b细胞的功能中起作用。编码该基因的染色体区域异常与非霍奇金淋巴瘤和多发性骨髓瘤有关[由RefSeq提供，2009年4月]
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. [provided by RefSeq, Apr 2009]