FOXL2 C134W

FOXL2基因上的变异c134w在成人粒细胞肿瘤中具有高频率(95-97%),成人粒细胞肿瘤占卵巢癌的5%。由于突变的频率很高,未来的治疗方法可能会针对这一明显的机制。然而,这种突变的后果仍然未知。
The variant C134W on the FOXL2 gene was revealed to have a high frequency (95-97%) in the adult form of granulosa cell tumors that comprises 5% of ovarian cancers. Due to the mutation's high frequency, future therapeutics might target for this single apparent mechanism. However, the consequence of this mutation remain unknown.

别名

突变位点

Ref. Build: GRCh37   Ensembl Version: 75
Chr.StartStopRef. sVar. Bases
3138665163138665163GC
Transcript
ENST00000330315.3

基因序列

NC_000003.11:g.138665163G>003eC