MCL1

该基因编码一种抗凋亡蛋白，属于bcl-2家族。选择性剪接导致多个转录变体。最长的基因产物（亚型1）通过抑制细胞凋亡来增强细胞存活，而交替剪接的较短的基因产物（亚型2和亚型3）则促进细胞凋亡并诱导死亡。[由RefSeq提供，2010年10月]
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]