NCOA2 HEY1-NCOA2 fusion

Hey1-NCOA2是间充质软骨肉瘤中一种特殊的复发性易位。由此产生的嵌合转录因子包括Hey1 DNA结合域（外显子1-4）和两个激活域以及一个来自ncoa2（外显子13-23）的组蛋白甲基转移酶相互作用域。
HEY1-NCOA2 is a specific and recurrent translocation in mesenchymal chondrosarcoma. The resulting chimeric transcription factor consists of the HEY1 DNA binding domain (exons 1-4) and two activating domains and a histone methyltransferase-interacting domain from NCOA2 (exon 13-23).