NEIL1

该基因是编码dna糖基化酶的nei内切酶viii样基因家族的成员。编码的酶参与DNA修复途径，通过去除碱基，主要是氧化嘧啶，启动碱基切除修复。已发现该基因编码不同亚型的多个转录变体。[ RefSeq，FEB 2012 ]提供
This gene is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]