RIPK2

该基因编码丝氨酸/苏氨酸蛋白激酶受体相互作用蛋白家族的一个成员。编码蛋白包含一个c末端caspase激活和募集域(card),是先天性和适应性免疫途径中信号复合物的组成部分。它是一种有效的nf-kappab激活剂和多种刺激下的细胞凋亡诱导剂。[由RefSeq提供,2008年7月]
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. [provided by RefSeq, Jul 2008]

别名

CCK,RICK,RIP2,CARD3,GIG30,CARDIAK

基因id

Chromosome:8 Start: 90769335 End: 90803292 Strand: 

药物

突变与药物

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相关基因检测

genes