RPS6KB1

该基因编码丝氨酸/苏氨酸激酶核糖体s6激酶家族的一个成员。编码的蛋白质对mtor（雷帕霉素的哺乳动物靶点）信号作出反应，促进蛋白质合成、细胞生长和细胞增殖。这种基因的活性与人类癌症有关。另外还观察到了剪接的转录变体。使用替代的翻译起始位点可导致具有较长或较短N-末端的亚型，其亚细胞定位可能不同。这个基因在17号染色体上有两个假基因。[由RefSeq提供，2013年1月]
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]