ULK4

该基因编码一个unc-51样丝氨酸/苏氨酸激酶（stk）家族成员。这个蛋白家族的成员在神经元生长和内吞过程中发挥作用。编码蛋白可能参与轴突分支、轴突延长和神经元迁移。全基因组相关研究（gwas）表明该基因的变异与血压和高血压有关。这个基因的序列变异也可能与精神疾病有关，包括精神分裂症和双相情感障碍与该基因相关的假基因已被鉴定，位于15号染色体上。[由RefSeq提供，2016年7月]
This gene encodes a member of the unc-51-like serine/threonine kinase (STK) family. Members of this protein family play a role in neuronal growth and endocytosis. The encoded protein is likely involved in neurite branching, neurite elongation and neuronal migration. Genome-wide association studies (GWAS) indicate an association of variations in this gene with blood pressure and hypertension. Sequence variations in this gene may also be be associated with psychiatric disorders, including schizophrenia and bipolar disorder. Pseudogenes associated with this gene have been identified and are located on chromosome 15. [provided by RefSeq, Jul 2016]