WDR5

这个基因编码WD重复蛋白家族的一个成员。WD重复是大约40个氨基酸的最小保守区域，通常由GLY HIT和Trp ASP（GH-WD）包围，这可能促进异源三聚体或多蛋白复合物的形成。该家族成员参与多种细胞过程，包括细胞周期进程、信号转导、凋亡和基因调控这种蛋白质含有7个WD重复序列。另外，编码相同蛋白质的剪接转录变体已经被鉴定。[由RefSeq提供，2008年7月]
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]