WT1 EXON 7 MUTATION

WT1外显子7突变在急性髓性白血病中有复发性。许多来源已经研究了这些基因的预后影响，同意突变的外显子7队列与较差的总生存率和一些不良的预后结果相关。这可能是由于wt1突变肿瘤对化疗反应不佳所致。
WT1 exon 7 mutations have been shown to be recurrent in acute myeloid leukemia. Many sources have examined the prognostic impact of these, agreeing that the mutant exon 7 cohort is correlated with worse overall survival and a number of poor prognistic outcomes. This may be the result of an overall poor response to chemotherapy from WT1 mutant tumors.