Q399R 基因突变 XRCC1癌基因 - 癌症123

基因突变

XRCC1 突变位点基因序列 XRCC1 Q399R xrcc1 q399r种系多态性（nm_.2:c.1196a\u003eg）与NSCLC患者更好的预后和宫颈癌患者对化疗的反应增加相关。 XRCC1 Q399R germline polymorphism (NM_006297.2:c.1196A\u003eG) is associated with better outcome for patients with NSCLC and increased response to chemotherapy for patients with cervical cancer.

别名

GLN399ARG,RS25487
Allele Registry ID：CA9488516
ClinVar ID：225976

突变位点

Ref. Build: GRCh37 Ensembl Version: 75

Chr.	Start	Stop	Ref. s	Var. Bases
19	44055726	44055726	T	C
Transcript
ENST00000262887.5

基因序列

NM_006297.2:c.1196A>003eG
NP_006288.2:p.Gln399Arg
NC_000019.9:g.44055726T>003eC
ENST00000262887.5:c.1196A>003eG